Entité de rattachement
Exploration, Espèces et Evolution (3E)

Contact

Courriel
nicolas.puillandre [at] mnhn.fr
Téléphone
01 40 79 31 66
Adresse(s)

43 rue Cuvier
CP26
75005 Paris

Responsabilités dans l'unité

Responsable de l’équipe 3E 

Présentation

Bref CV

Current position : Maître de Conférence, MNHN
Qualification : Ph.D., MNHN of Paris (2008) – Integrative taxonomy of the Turridae : phylogeny, species delimitation and barcoding.
Professional background :

  •  Post-doc, CNRS/MNHN (2012). Impact of the taxonomy on conservation programs.
  •  Post-doc, Atheris Laboratories (2011). DNA markers for deep phylogeny analyses in Conoidea.
  •  Post-doc, CNRS/MNHN (2010-2011). Managment of the MarBOL (Marine Barcode of Life) project.
  •  Post-doc, University of Utah (2008-2009). Species diversity within Conus and conotoxin evolution.

 Oceanographic expeditions

  •  Madang 2012 : Papua-New-Guinea. Marine Biodiversity Workshop. 03/11 – 16/12/2012.
  •  Guadeloupe 2012 : Guadeloupe. Marine Biodiversity Workshop. 14/06 – 28/06/2012.
  •  Atimo Vatae 2010 : Madagascar. Marine Biodiversity Workshop. 04/25 – 05/18 2010.
  •  Miriky 2009 : Madagascar. Collection of deap-sea organisms. 06/23 – 07/04 2009.
  •  Aurora 2007 : Philippines. Collection of deap-sea organisms. 05/20 – 06/05 2007.
  •  Santo 2006 : Vanuatu. Marine Biodiversity Workshop. 09/05 – 10/20 2006.

Associate editor : Journal of Molluscan Studies, Molecular Ecology Resources.

Research Interest

Bandeau recherches PUILLANDRE © MNHN

Phylogeny, species delimitation, and character evolution

My main reasearch interest is on developing integrative taxonomic approaches to analyze the species diversity, the phylogenetic relationships between species, and their interactions with the environment. Although specialized in the analysis of DNA variability and molecular systematic, my concern is also in developing complementary approaches to propose robust hypotheses based on several characters and criteria.
I am currently working on marine molluscs of the superfamily Conoidea (CONOTAX project).

This hyperdiverse group is a real challenge for taxonomists and molecular approaches have proved useful in proposing robust hypotheses on both species delimitation and phylogenetic relationships. These hypotheses are placed in an integrative framework, as others characters (morphology, anatomy or ecology) are analyzed. The strength of the results also relies on the collaborative aspect : anatomists, morphologists, biochimists, phylogeneticians,etc are all involved in the project. Actually, the interest of the Conoideans, illustrated by the results obtained with the genus Conus, does not only concern their hyperdiversity and their utility as a model to study speciation and diversification pattern in a marine environment, but also on the evolution of the toxins they use to capture their prey. As a result to the adaptation to their environment (and especially to new prey), these toxins (named « conotoxins » for the genus Conus) are particularly diverse, and their evolution is driven by several biochemical and molecular mechanisms. These toxins are moreover of particular interest in medecine, as some have already revealed their potential as therapeuthic drugs. Combining molecular, morphological, anatomical and toxinology approaches also provides a robust framework to analyse the evolution of the group, and in particular the factors that drove their exceptional diversification.

Defining species and their relationships are thus not only interesting for taxonomists, but also for setting up subsequent analysis both for theorical consideration (definition of species, speciation) and concrete applications (conservation biology, interaction with the environment, character evolution, discovery of new drugs,etc).

 

Projet HYPERDIVERSE, Les clés du succès évolutif: démêler les moteurs de l’hyperdiversification, projet  financé par l’ERC

Le projet HYPERDIVERSE, financé par l’ERC et porté par Nicolas Puillandre (ISYEB), a officiellement démarré le 1er octobre 2020, pour une durée de 5 ans. L’objectif du projet est de comprendre comment les néogastéropodes, un groupe de gastéropodes marins prédateurs, ont pu se diversifier autant : on connait 15000 espèces, mais il y en aurait au moins le double attendant d’être découvertes dans les océans. Ces prédateurs ont développé des stratégies de capture de proies faisant intervenir des composés moléculaires telles que des neurotoxines, des anticoagulants ou des anesthésiants. Le projet se propose de reconstruire une phylogénie du groupe, et de tester des hypothèses liées aux processus de diversification, avec des approches phénotypiques, génomiques, transcriptomiques et protéomiques. Si vous voulez en apprendre plus sur le projet et sur ces fascinants mollusques, rendez-vous sur :

 

 

 

Publications

2025
  • Aurélie Lacoeuilhe, Denys Gaël P. J., Dupont Pascal, Archambeau Anne-Sophie, Bed’hom Bertrand, Bouix Thomas, Brisset Julien, Cammas Maxime, Dettaï Agnès, Dusoulier François, Gachon Claire M. M., Gargominy Olivier, Gaudeul Myriam, Haÿ Vincent, Hérard Katia et al., 2025Référentiel des séquences génétiques des espèces de France : note pour la mise en place d’un nouvel outil national. , , p. 35
  • Fedosov Alexander, Ratti Claudia, Kantor Yuri & Puillandre Nicolas, 2025The Conasprella orbignyi (Gastropoda: Conidae) Complex Revisited: New Species Revealed by Increased Sampling. Malacologia vol. 67, 1-2,
    ISSN
    0076-2997
  • Lemarcis Thomas, Blin Amandine, Cariou Marie, Derzelle Alessandro, Farhat Sarah, Fedosov Alexander, Zaharias Paul, Zuccon Dario & Puillandre Nicolas, janvier 2025Too Far From Relatives? Impact of the Genetic Distance on the Success of Exon Capture in Phylogenomics. Molecular Ecology Resources , , e14064
    ISSN
    1755-098X, 1755-0998
2024
  • Lemarcis Thomas & Puillandre Nicolas, avril 2024Phylogeny of the neogastropods : methodological developments and evaluation of the success of the exon capture approach, Phylogénie des néogastéropodes : d??veloppements méthodologiques et évaluation du succès de l’approche par capture d’exons. The neogastropods (Mollusca, Neogastropoda) constitute a hyperdiversified group of marine predators, which includes more than… , , Issue: 2024MNHN0005
  • Lemarcis Thomas & Puillandre Nicolas, avril 2024Phylogeny of the neogastropods : methodological developments and evaluation of the success of the exon capture approach, Phylogénie des néogastéropodes : développements méthodologiques et évaluation du succès de l’approche par capture d’exons. , , Issue: 2024MNHN0005
  • Fedosov Alexander, Zaharias Paul, Lemarcis Thomas, Modica Maria, Holford Mandë, Oliverio Marco, Kantor Yuri & Puillandre Nicolas, mars 2024Phylogenomics of Neogastropoda: the backbone hidden in the bush. Abstract The molluskan order Neogastropoda encompasses over 15,000 almost exclusively marine species playing important roles in… Systematic Biology vol. 73, n° 3, p. 521-531 ISBN: 1063-5157 Publisher: Oxford University Press (OUP) Type: 10.1093/sysbio/syae010
    ISSN
    1063-5157, 1076-836X
  • Ringeval Allan, Farhat Sarah, Fedosov Alexander, Gerdol Marco, Greco Samuele, Mary Lou, Modica Maria & Puillandre Nicolas, mars 2024DeTox: a pipeline for the detection of toxins in venomous organisms. Venomous organisms have independently evolved the ability to produce toxins 101 times during their evolutionary history,… Briefings in Bioinformatics vol. 25, n° 2, bbae094 ISBN: 1467-5463 Publisher: Oxford University Press (OUP) Type: 10.1093/bib/bbae094
    ISSN
    1477-4054
  • Fedosov Alexander, Puillandre Nicolas, Fischell Frank, Patmanidis Stefanos, Miralles Aurélien & Vences Miguel, 2024« DNA Barcode-Based Species Diagnosis with MolD » in DNA Barcoding.. vol. 2744, , p. 297-311 Series Title: Methods in Molecular Biology
    ISBN
    978-1-07-163580-3 978-1-07-163581-0
  • Kantor Yuri, Bouchet Philippe, Fedosov Alexander, Puillandre Nicolas & Zaharias Paul, 2024Generic revision of the recent turridae (neogastropoda: Conoidea). Journal of Molluscan Studies , , ISBN: 0260-1230 Publisher: Oxford University Press (OUP)
  • Nocella Elisa, Fassio Giulia, Zuccon Dario, Puillandre Nicolas, Modica Maria Vittoria & Oliverio Marco, 2024From coral reefs into the abyss: the evolution of corallivory in the Coralliophilinae (Neogastropoda, Muricidae). Coral Reefs , ,
    ISSN
    0722-4028, 1432-0975