Entité de rattachement
Atelier de bio-informatique (ABI)
Recherches
Habilité(e) à diriger des recherches

Contact

Courriel
mathilde.carpentier [at] mnhn.fr
Adresse(s)

45 rue Buffon
CP50
75005 Paris

Responsabilités dans l'unité

Responsable de l’équipe ABI avec Lucie Bittner

Enseignements

Présentation

 

Positions


Interests in Biology

Keywords

  • Protein Structure Evolution, Protein Alignment Algorithm, Structural Bioinformatics, Virus, Metaviromics, Computational biology, evolution, bioinformatics.


After a PhD in bioinformatics on protein structural comparison and classification (2001-2005) at Université Pierre and Marie Curie (UPMC, Paris), I have developed skills in viral metagenomics during my post-doctoral fellowship (ATER, 2005-2006) at Université Denis Diderot (Paris). Since I have been recruted at UPMC (2006), and I have divided my time between teaching algorithmic, programming languages and bioinformatics to students in computer science and students in biology, while performing research in various fields of bioinformatics. I have spent 6 months in 2007 in Stanford (California, USA) as invited researcher at Michael Levitt Lab, working on protein structural classification in order to build a database for fold recognition. I have been the principal investigator of a grant for preliminary studies (PEPS BMI 2013 and 2014) for oceanic metaviromics annotation and analyses presented in a conference and resulted in a publication. I have published several major articles on protein structure analyses as well.

 

Publications

 


Supplementary Materials of some articles


Where and when

  • 2016-now : Assistant professor, ISYEB UMR 7205, Sorbonne University, Museum d’Histoire Naturelle (Paris, France)..
  • 2010-16 Assistant professor, IMPMC UMR 7590, University Pierre and Marie Curie (Paris, France).
  • 2007 Invited scholar at M. Levitt Team (CBS, Stanford, CA)
  • 2006-2010: Assistant professor, Analytical Genomics laboratory, University Paris 6 (UPMC).
  • 2005-2006: postdoc laboratory Modeling in integrated Biology, University D. Diderot (Paris 7).
  • 2002-2005: PhD with Joël Pothier & Pierre Netter (UPMC ; ABI).


Teaching

I teach algorithms, programming languages  and bioinformatics at l’ UFR d’Ingénierie

LOGO ATELIER DE BIO INFORMATIQUE

 

Publications

2023
  • Carpentier Mathilde, 2023La structure des protéines et son évolution. HDR. , , Habilitation à diriger des recherches tex.hal_id: tel-04076823 tex.hal_version: v1
  • Carpentier Mathilde & préciser A., 2023Soutenance HDR - Protein Structure and Evolution, La structure des protéines et son évolution. , , phd
  • Romei Martin, Carpentier Mathilde, Chomilier Jacques & Lecointre Guillaume, 2023Origins and Functional Significance of Eukaryotic Protein Folds. Journal of Molecular Evolution vol. 91, n° 6, p. 854-864
    ISSN
    0022-2844, 1432-1432
2022
  • Romei Martin, Sapriel Guillaume, Imbert Pierre, Jamay Theo, Chomilier Jacques, Lecointre Guillaume & Carpentier Mathilde, 2022Protein folds as synapomorphies of the tree of life. Evolution; international journal of organic evolution vol. 76, n° 8, p. 1706-1719 tex.earlyaccessdate: JUL 2022 tex.eissn: 1558-5646 tex.unique-id: WOS:000823430400001
    ISSN
    0014-3820
  • Sapriel Guillaume, Imbert Pierre, Carpentier Mathilde, Chomilier Jacques, Lecointre Guillaume & Romei Martin, 2022Are protein folds reliable phylogenetic markers?. , , dir. Christophe Dessimoz and Marc Robinson-Rechavi tex.hal_id: hal-03959674 tex.hal_version: v1 tex.howpublished: Mathematical and Computational Evolutionary Biology
2021
  • Carpentier Mathilde & Chomilier Jacques, 2021« Impact of a Point Mutation in a Protein Structure » in Systematics and the Exploration of Life.. , , dir. Wiley p. 17-31
    ISBN
    978-1-119-47687-0
2020
  • Carpentier Mathilde & Chomilier Jacques, 2020Analyses of displacements resulting from a point mutation in proteins. Journal of Structural Biology vol. 211, n° 2, p. 107543
    ISSN
    10478477
2019
  • Carpentier Mathilde & Chomilier Jacques, octobre 2019Protein multiple alignments: sequence-based versus structure-based programs. Bioinformatics (Oxford, England) vol. 35, n° 20, p. 3970-3980
    ISSN
    1367-4803, 1460-2059
  • Chomilier Jacques & Carpentier Mathilde, avril 2019Protein Multiple Alignments: Sequence-based vs Structure-based Programs. Motivation: Multiple sequence alignment programs have proved to be very useful and have already been evaluated in the… Bioinformatics (Oxford, England) vol. 35, n° 20, p. 3970-3980